We investigate mechanobiology processes at the single-molecular, molecular assembly, and cellular level. We use optical tweezers to reveal interactions between individual nucleic acid structures and motor proteins (e.g. polymerases) from mechanical perspectives. At the cellular level, we strive to probe the effect of molecular machineries such as protein aggregates and organelles on cell mechanics such as migrations and divisions.
Dr. Mao's Lab Website

Dr. Mao's Bibliography