We investigate the mechanisms underlying neurological disability in central nervous system diseases like multiple sclerosis. The laboratory employs modern techniques to address hypothesis driven studies using human samples, animal models and in vitro methods.
My laboratory’s research focuses on comparative neurobiology with an emphasis on aging, neuroinflammation, and neurodegenerative diseases (e.g., Alzheimer’s and Parkinson’s diseases). Using an evolutionary perspective, we investigate neurological variances across species, particularly nonhuman primates, as possible mechanisms of humans’ unique vulnerability to aging and neurodegeneration and human-specific cognitive specializations.
We investigate the neuroanatomical bases of what it means to be human. We use a comparative approach to understanding how the human brain differs from other species, including our susceptibility to neuropathological processes such as Alzheimer's disease.
We investigate the protein complexes and mechanisms that regulate genome organization throughout the cell cycle, and we study the consequences of disrupting DNA organization during development and for disease pathogenesis. We also study the role of retrotransposons in DNA organization, development and disease pathogenesis.
Our lab develps DNA-based nanoscale lipid bilayer mimetics for the structure determination of membrane proteins by cryo-electron microscopy. Moreover, we study mechanical properties of tightly bent DNA that govern biological processes including transcription, gene regulation and packing in the nucleus.
We investigate the neural basis of dysautonomia in autism spectrum disorder. Our lab uses systems and behavioral neuroscience to define the brain-body connection. The goal of this work is to transform how we diagnose and treat neurodevelopmental disabilities and other neuropsychiatric diseases.
Explore how an M.B.A. from Kent State can elevate your career. Join us on April 22 for a live webinar to learn about program options, admissions tips, and how our M.B.A. prepares you for leadership in today’s business world. Whether you're ready to apply or just starting your search, this session is for you.
