Piet, Richard
Rosen, Merri
Dutta, Ranjan
We investigate the mechanisms underlying neurological disability in central nervous system diseases like multiple sclerosis. The laboratory employs modern techniques to address hypothesis driven studies using human samples, animal models and in vitro methods.
Edler, Melissa
My laboratory’s research focuses on comparative neurobiology with an emphasis on aging, neuroinflammation, and neurodegenerative diseases (e.g., Alzheimer’s and Parkinson’s diseases). Using an evolutionary perspective, we investigate neurological variances across species, particularly nonhuman primates, as possible mechanisms of humans’ unique vulnerability to aging and neurodegeneration and human-specific cognitive specializations.
Lu, Yong
Takeshita, Rafaela
Raghanti, Mary Ann
We investigate the neuroanatomical bases of what it means to be human. We use a comparative approach to understanding how the human brain differs from other species, including our susceptibility to neuropathological processes such as Alzheimer's disease.
Longworth, Michelle
We investigate the protein complexes and mechanisms that regulate genome organization throughout the cell cycle, and we study the consequences of disrupting DNA organization during development and for disease pathogenesis. We also study the role of retrotransposons in DNA organization, development and disease pathogenesis.
Schmidt, Thorsten
Our lab develps DNA-based nanoscale lipid bilayer mimetics for the structure determination of membrane proteins by cryo-electron microscopy. Moreover, we study mechanical properties of tightly bent DNA that govern biological processes including transcription, gene regulation and packing in the nucleus.